Understanding DHODH Inhibition

Therapeutic Mechanisms of Action of JBZ-001

On top of the expected nucleotide depletion-induced cell stress, our DHODH inhibitor, JBZ-001, displays multiple mechanisms of action, broadening its potential clinical applications, including:

Explore JBZ-001’s Therapeutic Effects:

Metabolic Disruption
Myeloid Cell Differentiation
Increased CD38 Expression
Increased CD47 Expression